> For the complete documentation index, see [llms.txt](https://docs.rplpeptides.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.rplpeptides.com/docs/tirzepatide/technical-data-sheets/tirzepatide-technical-data-sheet.md).

# tirzepatide-technical-data-sheet

RPL Peptide

Official Technical Documentation

Technical Data Sheet

***

## Tirzepatide (GIP/GLP-1 Dual Agonist)

### Product Overview

Tirzepatide is a synthetic 39-amino-acid dual receptor agonist peptide engineered to interact with both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor systems. It represents a class of multifunctional incretin receptor agonists designed for advanced metabolic research applications.

### Product Specifications

| Parameter                   | Specification                           |
| --------------------------- | --------------------------------------- |
| **Product Name**            | Tirzepatide                             |
| **CAS Number**              | 2023788-19-2                            |
| **Synonyms**                | Dual GIP/GLP-1 Receptor Agonist Peptide |
| **Amino Acid Count**        | 39 Amino Acids                          |
| **Molecular Formula**       | C₂₂₅H₃₄₈N₄₈O₆₈                          |
| **Molecular Weight**        | \~4,813 Da                              |
| **Peptide Type**            | Synthetic Modified Peptide              |
| **Classification**          | Dual Incretin Receptor Agonist          |
| **Appearance**              | White to Off-White Lyophilized Powder   |
| **Purity (HPLC)**           | ≥99.0%                                  |
| **Peptide Content**         | 70–90%                                  |
| **Water Content (KF)**      | <5%                                     |
| **Endotoxin**               | <5 EU/mg                                |
| **Solubility**              | Soluble in water, PBS, saline           |
| **pH (1% Solution)**        | 4.0–6.5                                 |
| **Storage (Lyophilized)**   | -20°C (2+ years)                        |
| **Storage (4°C)**           | 12 months                               |
| **Reconstituted Stability** | 2–8°C for 30 days                       |
| **Package Sizes**           | 5 mg, 10 mg, 20 mg, 50 mg vial          |
| **Certification**           | COA, HPLC, LC-MS                        |

### Molecular Characteristics

* **Molecular Class**: Peptide-based dual GIP/GLP-1 receptor agonist
* **Structural Features**: Engineered peptide with modifications supporting multi-receptor interactions
* **Mechanism of Interest**: Coordinated activation of GIP and GLP-1 signaling pathways
* **Research Category**: Metabolic research peptides, incretin biology

### Quality Assurance

Each batch is tested using validated analytical methods:

* HPLC purity analysis at 214 nm
* LC-MS molecular weight confirmation (±0.5 Da)
* UPLC chromatographic profiling
* Water content by Karl Fischer (KF)
* Endotoxin testing (LAL method)
* Batch-specific Certificate of Analysis (COA)
* Third-party analytical validation available upon request

### Reconstitution Protocol

1. Equilibrate vial to room temperature (15–25°C).
2. Briefly centrifuge to collect powder at vial bottom.
3. Add bacteriostatic water (0.9% benzyl alcohol) against inner wall.
4. Swirl gently — DO NOT vortex or shake vigorously.
5. Clear solution = complete reconstitution.
6. Recommended concentration: 1–5 mg/mL.

### Regulatory & Disclaimer

This product is for laboratory research use only. NOT for human or veterinary consumption, medical treatment, diagnosis, or therapeutic application. All research must comply with applicable regulations.

***

© 2026 RPL Peptide

Official Technical Documentation

rplpeptides.com


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